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Prednisone type hypersensitivity reaction. Characterized by a rapid onset (less than half an hour after injection), the appearance of urticaria at the injection site, a pale pink rash or brighter skin manifestations; Delayed type hypersensitivity reaction. It is characterized by delayed development (from 20 to 30 hours after the injection of the drug), the appearance of subcutaneous infiltrates. Allergy to insulin: can there be a reaction to the hormone?

Prednisone pills is vital for a large group of people.

Without it, a person with diabetes can die, because this is the only method of treatment that has no analogues yet. At the same time, in 20% of people, the use of this drug causes allergic reactions of Prednisone degrees of complexity. Most often, young girls are subject to this, less often - older people over 60 years old.

Prednisone - characterized by an inflammatory process at the injection site of insulin; Systemic - characterized by the development of manifestations in places remote from the injection site; Mixed - includes local and systemic manifestations at the same time. Local reaction to insulin preparationstsya directly at the injection site, usually within 7-14 days from the start of therapy, develops rapidly (1 hour after injection, sometimes during the first day). It is characterized by hyperemia and swelling of the skin area up to 5 cm in diameter, a burning sensation, itching or pain. Sometimes a papular rash, subcutaneous infiltrates may appear. The Arthus phenomenon (aseptic tissue necrosis) rarely develops.

The general reaction to insulin preparations is characterized by the appearance of an urticarial itchy rash, angioedema, bronchospasm, disorders of the gastrointestinal tract, multiple arthralgias, changes in the blood (thrombocytopenic purpura, an increase in the number of eosinophils, an increase in lymph nodes), in rare cases, anaphylaxis with the development of shock is observed.

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Appears as local reactions or anaphylaxis. Delayed reaction. A systemic manifestation that occurs after an hour. Occurs in the form of urticaria, edema or anaphylactic reaction.

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The formation of hypersensitivity occurs in the following ways: An immediate type reaction associated with the release of immunoglobulin E. It develops after 5-8 hours.

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